Liverpool manager Brendan Rodgers will bring back all his big names for Sunday's game.
Steven Gerrard, Luis Suarez, Glen Johnson, Martin Skrtel, Daniel Agger, Joe Allen and Martin Kelly were all rested for Thursday night's 5-3 Europa League win at Young Boys but will return as the Reds go looking for their first Premier League victory of the season.
Forwards Fabio Borini and Raheem Sterling, substitutes in Switzerland, are likely to start while midfielder Jonjo Shelvey pressed his claims for inclusion with a two-goal second-half cameo.
Manchester United winger Ashley Young will miss out after being ruled out for a further two to three weeks with knee cartilage trouble.
Wayne Rooney will also be absent due to a gashed thigh despite reports he was due to make an earlier-than-expected comeback.
Darren Fletcher, who came on as a substitute in the Champions League win over Galatasaray in midweek having recovered from a chronic bowel condition, is not being considered for a return to the starting line-up with Sir Alex Ferguson instead pin-pointing next Wednesday's Capital One Cup clash with Newcastle.
Liverpool (from): Reina, Kelly, Agger, Skrtel, Johnson, Gerrard, Allen, Shelvey, Suarez , Borini, Sterling, Jones, Carragher, Coates, Enrique, Henderson, Sahin, Downing, Assaidi.
United (from): Lindegaard, De Gea, Rafael, Ferdinand, Evans, Vidic, Evra, Buttner, Valencia, Scholes, Fletcher, Powell, Carrick, Cleverley, Anderson, Giggs, Nani, Van Persie, Hernandez, Welbeck.